Chameleonic properties make large molecules into possible drugs
In a paper published today in Nature Chemical Biology, a team of researchers from Uppsala University, the Broad Institute of MIT, Harvard, and AstraZeneca are presenting new insights into how...
View ArticleA step toward a UTI treatment that could thwart bacterial drug resistance
This spring, a Pennsylvania woman who developed a urinary tract infection (UTI) became the first patient in the U.S. reported to have a bacterial infection resistant to colistin, an antibiotic of last...
View ArticleNew discovery could help oral medicines work better
A team of researchers from the University of Minnesota and The Dow Chemical Company have discovered a new method for customizing ingredients that help oral medications dissolve in the body and be...
View ArticleNew advance in RNA studies holds out hope for cancer drug development
An international research team led by the University of Leicester has made a breakthrough advance that could pave a new route for the development of anti-cancer drugs.
View ArticleMolecules change shape when wet
In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers led by Melanie Schnell from the Max Planck Institute for the Structure and...
View ArticleNew device to help police catch cocaine-using drivers
Over 8,000 people were arrested in England and Wales for driving under the influence of drugs in the year to April 2016. In fact, 60% of all those stopped by police under suspicion of drug-driving test...
View ArticleNew computational method to create drugs more efficiently
Researchers of the University of Barcelona have developed a more efficient computational method to identify new drugs. The study, published in the scientific journal Nature Chemistry, proposes a new...
View ArticleNon-ambient conditions in the investigation and manufacturing of drug forms
To become a drug, a pharmacologically active compound must be prepared in a specific form. This form must be robust during manufacturing, packaging, storage and transport, and must administer the...
View ArticleChemists unveil versatile new method for making chiral drug molecules
Chemists at The Scripps Research Institute (TSRI) have invented a new technique for constructing chiral drug molecules.
View ArticleNew algorithms may revolutionize drug discoveries—and our understanding of life
A new set of machine learning algorithms developed by U of T researchers that can generate 3D structures of tiny protein molecules may revolutionize the development of drug therapies for a range of...
View ArticleDigital chemistry set reaches new heights with space launch
A University of Glasgow research project is set to get underway beyond the earth's atmosphere following a successful launch into space today (Wednesday 15 February).
View ArticleDNA computer brings 'intelligent drugs' a step closer
Researchers at Eindhoven University of Technology (TU/e) present a new method for controlled drug delivery into the bloodstream using DNA computers. In the journal Nature Communications, the team, led...
View ArticleVirus inspires new way to deliver cancer drugs
Drugs disguised as viruses are providing new weapons in the battle against cancer, promising greater accuracy and fewer side effects than chemotherapy.
View ArticleStudy says drugs could be developed cheaper and faster
Chemists at the University of Waterloo, SCIEX and Pfizer have discovered a new way to help the pharmaceutical industry identify and test new drugs, which could revolutionize drug development, and...
View ArticleResearchers push the limits of organic synthesis
A dendritic molecule is one that grows by branching in several directions from its center core. At each branching point, the molecule branches again into a new generation. These molecules can be used...
View ArticleNewly discovered malaria mechanism gives hope to pregnant women
Resistance to malaria drugs means that pregnant women are unable to overcome the anaemia caused by the malaria parasite – and their babies are born undersized. A study carried out at Karolinska...
View ArticleCutting-edge analysis reveals how different drugs interact with the same target
Osaka University-led researchers identified differences in how three drugs bind to tumor necrosis factor, a key mediator of inflammatory disease. The team used sedimentation velocity analytical...
View ArticleAntibody biosensor offers unlimited point-of-care drug monitoring
Being able to monitor drug concentration in the blood of a patient is an important aspect of any pharmaceutical treatment. However, this requires equipment and facilities that are often missing from...
View ArticleResearchers uncover new way to stimulate the body's immune response
IBM announced its researchers have identified a new way to trigger the body's immune response by using polymer-coated graphene sheets. The research was recently published in Nature Communications.
View ArticleNew approach set to make peptide stapling widely available
UK scientists have created a new method to structure peptides, which they say will be cheaper and make the process of using stapled peptides in drug discovery much more widely available.
View ArticleCommercializing structural biology knowledge can save money and speed drug...
HarkerBIO is a "shining star" in the growing biotech ecosystem taking shape on the Buffalo Niagara Medical Campus. The small structural biology company determines 3-D structures of proteins for drug...
View ArticleTechnology unlocks mold genomes for new drugs
Fungi are rich sources of natural molecules for drug discovery, but numerous challenges have pushed pharmaceutical companies away from tapping into this bounty. Now scientists at Northwestern...
View ArticleElectron caught in the act
Australia's fastest camera has revealed the time it takes for molecules to break apart.
View ArticleResearchers explore ways that a drug like Avandia can be made safer
With the heightened concerns over the dangerous side effects of the once-popular antidiabetic drug Avandia, researchers at The Scripps Research Institute (TSRI) in Jupiter, Florida, are working to...
View ArticleLarge, crystalline lipid scaffolds bring new possibilities to protein, drug...
Proteins and drugs are often attached to lipids to promote crystallization or ensure delivery to targeted tissues within the body, but only the smallest proteins and molecules fit within these fat...
View ArticleDesigning drugs aimed at a different part of life's code
Most drugs work by tinkering with the behavior of proteins. Like meddlesome coworkers, these molecules are designed to latch onto their target proteins and keep them from doing what they need to do.
View ArticleScientists develop potentially therapeutic gel, which detects nitric oxide,...
IBS scientists at the Center for Self-Assembly and Complexity, within the Institute for Basic Science (IBS), invented a hydrogel to fight rheumatoid arthritis and other diseases. Published in Advanced...
View ArticleQuest for new medicines could be helped by cell discovery
Scientists have made a key discovery that could speed up the production of cells in the lab for studying diseases such as multiple sclerosis and Parkinson's disease.
View ArticleRevolutionizing drug discovery with RNA in the spotlight
The rise of antibiotic resistance among common infectious bacteria is a worrisome health threat that has many scientists looking for a solution. Jennifer Hines, Ph.D., professor of chemistry and...
View ArticleEngineers make drug testing more efficient and affordable
McMaster University engineers have devised a way to make testing for new drugs more efficient and affordable, and reduce the time for helpful medications to reach the public.
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